Could Inflammation Be The Cause Of Myriad Chronic Conditions?
The 2017 clinical trial, called CANTOS (Canakinumab Anti-Inflammatory Thrombosis Outcomes Study), is the result of a long-term collaboration between Paul Ridker and Peter Libby, who suspected as long ago as the 1980s that inflammation played a role in cardiovascular disease. Libby further found that IL-1, by altering gene expression in local blood vessel cells, amplifies its signal at the site of the disease. Roni Nowarski, assistant professor of neurology and immunology, explains that inflammation is important across a range of seemingly distinct pathologies because immune cells are everywhere, even resident in organs, where they play an important role in monitoring and maintaining health.
Source: harvardmagazine.com